Abstract Hydroxyapatite powder Ca10(PO4)6(OH)2 was prepared locally from the bones of the cow, and characterization the powder as well as studied purity. A composite of hydroxyapatite-zirconia was also prepared with a percentage of zirconia 0,5,10,15,20,25% wt . Use polyethylene glycol as a binder with 1% wt by dissolving polyethylene glycol with ethanol (1g: 100ml) at 40 °C and using a magnetic stirrer to obtain a homogeneous solution for the material. Then dry the powder and press the samples, then heat treatment at 1350 ° C for three hours. The physical and mechanical properties studied were density, porosity, water absorption ratio, hardness and compression resistance, as well as X-ray diffraction and X-ray florescence.