Abstract

Background: Thyroid hormone (TH) deficiencies or hypothyroidism, impact a significant portion of the world's population. This study investigates the connection between platelet-associated immunoglobulins (PAIgG) and thyroid dysfunction. Materials and Methods: From April to December 2022, a multicenter study with 55 patients suffering from thyroid issues was carried out. Analyses were conducted (ANA, PAIgG) and therapy regimens. The control group consisted of people with thyroid problems who did not receive medical intervention. With SPSS, statistical analyses were carried out. Results: Female sex and ANA positive among thyroid illness patients were substantially correlated (p = 0.007 and 0.04, respectively). While there were no discernible variations in platelet counts between the research groups, thyroid patients did have a numerical rise in PAIgG levels. Platelet counts improved after treatment for underlying thyroid problems. Conclusion: The study's impact on hemoglobin and platelet levels supports the conclusion that early detection and care of hypothyroidism are essential for averting negative outcomes. Research on thyroid anomalies and their clinical implications has to be furthered, and the multicenter method improves the generalizability of findings in this regard.