Abstract

Asthma is the hypersensitivity-reaction. Numerous elements were mentioned as being crucial in the pathogenicity of asthma. By using the ELISA technique on the sera of 100 asthmatics and 50 supposedly healthy controls, the amount of total IgE was measured, and the level of vitamin D3 was estimated using the same procedure on the subject sera (60 asthma-patient and 30 controls). According to this study, asthmatic patients' sera had significantly higher total IgE levels than control groups (P=0.001). Also, the study found that asthmatic patients' serum vitamin D levels declined significantly (P≤0.05) compared to the healthy control group. In addition, demonstrates decrease in vitamin D levels in severe asthma compared to moderate, mild asthma, and control at high significance (p= 0.001), helps to explain the relationship between vitamin d and asthma severity. Furthermore, Total IgE and Vit. D3 test found to be the ideal test for those with asthma.