Diarrhea has received much attention in recent years due to its biodegradable properties that having the second leading cause of death in children under 5 years' age. The current study, involved sampling and analyzing (121) subjects, (71) of them with diarrhea and (50) healthy control 25(50%) female & 25(50%) male at ages ranging from 2 months to 5 years. The electrolyte level (Na, K, Cl, Ca) were measured and complete blood count (CBC) to diagnose conditions, such as anemia, infection, and many other disorders. The modeled of cases classified according to type of feeding and water source. The results showed that combination of two mechanistically distinct of the disease formed are incorporation of significantly increased diarrhea or vomiting (gastroenteritis) can lead to electrolyte disturbances along with dehydration and anemia. Oral-fecal route of infection (contaminated water and food) leads to rapid dehydration and inability to absorb nutrients from food; survivors may have impaired growth and development, malnutrition, long-term GI disorders, reduced immunity and maybe death.